How CBD Aids In Endo Pain Relief & Cellular Repair

May’s modality of the month is brought to us by Mohnia Patel of Shanti Wellness. Mohnia grew up in her family's health food store. She has always been drawn to natural remedies by use of natural herbs and supplements which is what ultimately led her to quitting her corporate job and starting Shanti Wellness with her husband. During a darker period in her life she used CBD to help lift her out of this time. Her use of CBD brought her to the creation of her line of products, her goal was to help other people.


Let’s start with what CBD is. How does it differ from THC?

CBD stands for cannabidiol, the central cannabinoid found in cannabis and industrial hemp. Decades of research have concluded that, in a moderate dose, CBD can have numerous health benefits.

CBD and THC are both found in Hemp and Cannabis, CBD, unlike THC, is non-psychoactive, in plain terms CBD doesn't get you high while THC does. CBD also has therapeutic benefits ranging across a wide range of symptoms. It’s very good at reducing the intensity of pain!

How can CBD aid in treating endometriosis and its symptoms?

The following information is from a great article “Can CBD help treat endometriosis naturally?” on The ChalkBoard. I wouldn't skip over this section! “Scientists are enthusiastic about CBD and THC compounds because the recent discovery that the body’s natural endocannabinoid system is integral to the healthy functioning of the female reproductive tract.

In fact, imbalances in these neurotransmitters are often linked to reproductive complications and diseases — including endometriosis — and it seems that careful use of phytocannabinoid supplements, topicals, and suppositories could make a huge difference in the underlying imbalance. How? -CANNABINOIDS STOP CELL MULTIPLICATION Normally, your body has tools to prevent the growth of aberrant cells and to destroy them (apoptosis) before they become a problem. Unfortunately, apoptosis seems to be impaired in people who suffer from endometriosis and similar disorders. The endocannabinoid system is involved in apoptosis and stopping cell growth. Perhaps the most famous application of these effects is in cancer treatments. When certain cannabinoid receptors are activated (either by the body’s endocannabinoids or by plant-sourced THC), they can prevent cancer cells from multiplying. Similar research has shown that activating these receptors inhibits endometriotic tissue from proliferating in mice. -CBD PREVENTS CELL MIGRATION A frustrating problem for women who surgically remove their endometriotic lesions is that the endometriosis frequently comes back. However, scientists recently discovered that endocannabinoids are involved in regulating cell-migration. It turns out that molecules like CBD can stop endometriotic cells from migrating (by blocking the activation of the GPR18 receptor). However, molecules like THC that activate this receptor could potentially increase cell migration. This suggests that women who self-medicate with THC should consider counterbalancing its effects with CBD. -STARVING THE BLOODSUCKERS In order for anything to grow, it needs a supply of nutrients. Likewise, endometriotic lesions can only proliferate if they develop a network of blood vessels (vascularization) in order to receive the required nutrients. Although research on the influence of cannabinoids on endometriotic vascularization is limited, multiple studies have shown that both THC and CBD can inhibit vascularization of cancerous lesions. -CBD VS PAINFUL NERVES Some women suffer from deep-infiltrating endometriosis — a more painful form of endometriosis that embeds deeper into abdominal tissue. One reason these lesions might be more painful is that they contain a much higher density of nerves than other lesions. Endocannabinoids regulate nerve growth, and their receptors (CB1) are expressed on the nerves that innervate endometriotic lesions. Molecules like CBD interfere with innervation by preventing activation of this receptor. However, this might suggest that using THC without the counterbalancing effects of CBD could result in a long-term increase in endometriosis innervation -LIKE ADVIL WITHOUT THE SIDE-EFFECTS  NSAIDs like Advil are one of the most frequently-prescribed treatments for endometriosis. NSAIDs work by inhibiting certain enzymes (named COX-2) that contribute to inflammation. Unfortunately, NSAIDs thin your blood and can have gastrointestinal side effects because they also inhibit other enzymes (such as COX-1). It turns out that CBD’s anti-inflammatory effects come with fewer of these side-effects because it specifically inhibits COX-2 but not COX-1. -CANNABINOIDS CALM AN OVERACTIVE IMMUNE SYSTEM A large number of your body’s endocannabinoid receptors (CB2) are located on your immune system’s killer cells (macrophages). When these receptors are activated, they prevent macrophages from releasing inflammatory proteins (cytokines). People who suffer from endometriosis become hypersensitized to inflammatory toxins and signals. Fortunately, THC activates CB2 receptors, which is a large contributor to THC’s anti-inflammatory properties. This is useful for out of control inflammation caused by an overactive immune system — though depressing the immune system isn’t always desirable. -CBD + THC VS PAIN SIGNALS Nerves that innervate endometriotic lesions can increase the pain of endometriosis. These nerves also contain endocannabinoid receptors (CB1), and when THC activates this receptor it can help decrease pain. CBD also helps relieve feelings of pain, but through other targets. Most notably, CBD is capable of desensitizing the pain receptor TRPV1.”

When looking for a cbd product what should one look for?

Find a clean product with transparency about ingredients, formula and good customer service. For doses, its best to start with 1 mg for every 10lbs of body weight and increase/decrease from there. Remember to always listen to your body. For beginners, I recommend our Hemp CBD Tincture for mild to moderate symptoms OR our extra strength CBD oil softgels for more advanced users. In any case, our CBD balm is great for spot treatment of pain, especially muscle pain. 

What ingredients do you use?

We use organically grown Hemp from Colorado that is minimally processed to create a high-quality pesticide, solvent, and THC free Hemp CBD extract. This is then used to formulate our Tincture, Balm, and Softgels. Each product has a combination of ingredients that can be viewed under the ingredient section!


“This balm is so amazing! I love it. I use it for cramps or shoulder aches, my fiance even started taking it from our medicine cabinet to use after workouts.” -Emily

“This is my favorite CBD tincture. It really works and has a fresh peppermint taste (I like to add it to water). I have back pain and CBD has been such a game changer for me. It also helps with anxiety. Furthermore, I am proud to support a female owned and operated business.” -Amanda

“I have been suffering from anxiety for some time now. It started somewhere around college and I've been struggling to get a grip on it. I have been using CBD but wanted something more too. I saw this product on Shanti Wellness's Instagram and decided to give it a shot. Its natural and doesn't have any weird ingredients. It took about 3 weeks for me to feel it but WOW. I am so much less worrisome and anxious, I'm sleeping better and my husband even mentioned how much calmer and happier I seem! This is the only thing I added. I highly recommend taking this if you feel like you've tried everything else. I can't be without Tranquil anymore!” -Maria



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